Natural product-intermediate- 7Ethyl10hydroxycamptothecin(SN38)


Benenature code: BNO14
Botanical source: Nothapodytes Pittosporoides(Mappia) (Camptothecin)

Used part: stems and roots
Test Method: HPLC
Appearance: Light yellow crystal powder.

7-Ethyl-10-Hydroxycamptothecin(SN-38) is a semisynthetic analog of camptothecin in which the hydroxyl group at the C10 position and the ethyl group at the C7 position help to stabilize SN38 in physiological environments. Benenature’s SN38 route is as follows:

Mappia roots👉camptothecin👉10-Hydroxycamtpothecin👉SN38.

(SN-38) is a topoisomerase I inhibitor for anti-cancer therapy, the biologically active metabolite of Irinotecan HCl(CPT-11). SN-38 causes the strongest inhibition of DNA topoisomerase I, followed by CPT and then CPT-11.

Benenature keeps a sustainable supply of naturally sourced camptothecin and camptothecin derivatives including SN38. We recycle the extraction solvent with our unique recycling system.

Testing lab to control the quality of plant extracts and natural ingredients.
SN-38 single impurity<0.5% by HPLC.
roots of mappia
Sustainable origin of raw materials for camptothecin extraction.
Calibrated vacuum meter of extraction tank in the workshop of plant extract manufacturer.
Natural SN-38 originated from Mappia roots.
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Characteristic of Benenature 7-Ethyl-10-Hydroxycamptothecin

🌿100% Natural Camptothecin orginated.

🌿Single impurities strictly controlled: single impurity<0.5%.

🌿Purity of SN-38>99.00%, a choice to be a reference substance

🌿SN-38 is always in stock with bulk quantities.

Chemical Information of 7-ethyl-10-Hydroxycamptothecin

Chemical Structure:


Chemical Formula: C22H20N2O5

Structure 7-ethyl10hydroxycamptothecin(SN-38)

🍀Topoisomerase inhibitor for anticancer.


🍀Key raw material for Irinotecan Hydrochloride synthesis.


7-Ethyl-10-Hydroxycamptothecin is generally packed in two food-grade plastic bags with IATA required carton, net Weight:5.0kg/carton. At the same time, 1kg or 500g aluminum foil bag is available for your unique needs, Net Weight:5.0kg/IATA carton.Please store SN-38 in a cool and dry place, avoid direct sunlight.


Three years when sealed and properly stored.

Shelf Life

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