5 Top Andrographis Extract Manufacturers on the Global & China Market

The ongoing COVID‐19 crisis has brought the focus back to improving daily immune health like never before. During this time, there’s been a significant increase in demand for several immune‐strengthening supplements, ranging from vitamins to botanicals like Andrographis Extract.

What is Andrographis Extract? Andrographis Extract is a powder extracted from the herb Andrographis Paniculata Nees, the main ingredient is andrographolide. Andrographis extract is also named Andrographis Paniculata extract, Kalmegh extract, Fah Talai Jone extract, Green Chiretta extract, and Indian Echinacea extract. As we know, Andrographis extracts are applied widely in industries of pharmaceutical, nutraceutical, cosmeceutical, and animal health as the extract has antioxidant and anti-inflammatory effects.

However, there are many different manufacturers and suppliers of Andrographis extract on the market, numbers of manufacturers from India and China, numerous exporters from Asia, thousands of Andrographis extract traders worldwide. Hard to pick one? Consequently, how to make the best choice for Andrographis extract? You can use this information to make the best possible decision.

In this article, you will find the top companies in the world that provide the best Andrographis Extract on the market. All you need to do is check the information below and the websites of the companies that sell the extract that you may be looking for. You will find the essential information about each company and their extracts.
This article is composed of two parts. In the first part, here, you will find the top 5 Andrographis extract suppliers and manufacturers on the global market. Subsequently, you will find the top 6 manufacturers that locate in China. It is in your best interest to check all the options before you make your final decision.

Top 5 Andrographis Extract Suppliers on Global Market

In worldwide, giant manufacturers of botanical extracts are mainly distributed in the USA, Italy, and Germany. Such as Martin Bauer Group and Sabinsa, both have perfect products. As to India, suppliers are prosperous.

1. Sabinsa

Founded in 1988 by Muhammed Majeed, Ph.D., Sabinsa is a company dedicated to the principles of tradition, innovation, and research. Sabinsa Corporation is a manufacturer, supplier, and marketer of herbal extracts, cosmeceuticals, minerals, dietary supplements, and specialty fine chemicals. Over the past 30 years, Sabinsa has brought to market more than 100 standardized botanical extracts and privately funded several clinical studies in conjunction with prestigious institutions in support of these products. You can be sure that the focus of the company is on its clients. Their success and enormous experience are the best proof you will need. Sabinsa’s standardized Phytoextracts include:

Adhatoda Vasica Extract 1% vasicine 2% Total Alkaloids
Ashwagandha Root extract 7% wihanolides
Berberis Aristata Extract 97%berberine Chloride
Curcuma Longa Extract series,
Sesame extract
Rosemary extract
Pterocarpus extract series, and more.

Meanwhile, Sabinsa markets its Andrographis Paniculata extract under the trademark Panicin^TM, with the specification of andrographolide10%, andrographolide50%, and andrographolide90%. As to Andrographis Extract, Sabinsa is a giant. You can find all the information you need about each option on the company’s website.

2. Martin Bauer Group

Since 1930, Martin Bauer Group has stood for expertise in botanical products. With more than 20 manufacturing sites and sales units worldwide, Martin Bauer is absolutely the top giant of botanical extracts and natural ingredients. Martin Bauer is the one who started the Ginkgo biloba extracts in the early ages and spreads them around the world. Martin Bauer’s wide natural products line composed of

Naturfil: from nature to the consumer.
Atomized Dry Extracts: extracted and spray-drying fruits.
Steam Sterilized herbs in powder.

The automized dry extracts besides the ginkgo Biloba extract, for instance, have a wide range also:

Aloe vera extracts series
Artichoke leaf extract total polyphenols series
Buckthorn bark extract series
devil’s claw root extract series with harpagoside higher than 0.5%
Ginseng soluble
Horsechest nut seed extracts series
Olive leaf extract with Oleuropein series
Resveratrol NLT98%, quercetin, rutin and more.

As to Andrographis Paniculata (Burm f.) Nees Extract, Martin Bauer supports their customers with specifications: andrographolide 10% and andrographolide95% in the fields of

body natural defenses
Digestive function
Upper respiratory tract functionality
Carbohydrate metabolism.

With more than 90years of experience in herbal products, we believe that Martin Bauer works to maintain your competitive edge. For the products list and details, please email them as described on their website.

3. Layn Natural Ingredients

Two farmers Mr.Jiang and Mr.Yao started the Layn corp by providing botanical raw materials in the 1990s. Layn starts later than some of the herbal extract manufacturers from Shaanxi and Sichuan Province, but it becomes the first listed company in China’s botanical extract industry, and layn is still one of the top ones in this industry in China.

Layn Corp takes a great role in plant-based sweeteners, and Layn is FDA GRAS Affirmed for both Monk Fruit and Stevia extract. Firstly, Layn has dual harvests per year for both Monk Fruit and Stevia extract in Layn’s co-farming land. Secondly, Layn makes the Mogroside-v content increase from 0.3% to 0.5% in the natural Monk Fruit. Moreover, Layn’s 4^th generation facility is the world’s largest Stevia and Monk Fruit extract capacity. In addition, Layn opens Global Innovation Center in Shanghai, China, to support and meet global reformulation needs.

Besides the shinning nature-sourced sweeteners, Layn corp supplies natural ingredients for food and beverage, pet &animal nutrition, and nutraceuticals. Layn just released the SophorOx^TM for a healthy inflammatory response after the pandemic Covid-19. More and more people care about immune health as the outbreak of covid-19. Layn corps natural extracts line in immune health includes:

Andrographis Extract series with active ingredient andrographolide.
Echinacea Extract series of Polyphenols,
Ginger Extract with Gingerol series
Honeysuckle extract with different levels of Chlorogenic Acid
Sophora Japonica extract with Quercetin Anhydrous/quercetin dihydrate
Rhodiola Rosea Extract with Rosavins/Salidroside
And More…

As to Andrographis extract, Layn corp has a special feature as Guanxi is the top 2 origin place for herb Andrographis Paniculata Nees(Chuanxinlian in Pinyin). Layn takes good use of this sole advantage and seize a great market share of Andrographis Extract. Meanwhile, Layn offers a whole line of Andrographis extract with all the Specifications: Andrographolide5%, Andrographolide10%, Andrographolide30%, Andrographolide50%, and Andrographolide98%.

To keep up with the growing global demand worldwide, Layn corp set up subsidiary companies in both EU(Located in Italy), and the US in California. More and more details are available on layn’s website.

4. Natural Remedies

Natural Remedies can be back to 1950 and the founder is Mr. Shri. Ramlal Agarwal, named after Natural Remedies in 1998. the company introduced the herbal range of products for human healthcare in 2000. Till now, Natural Remedies deliver both animal and human healthcare products, combing their traditional Ayurveda knowledge and modern science.

For human healthcare care products, Natural Remedies offers some clinically tested ingredients, their branded ingredients are as follows:

BacoMind^® from Bacopa monnieri extracts with nice bioactive compounds for memory and cognitive abilities support.
GutGard^® from Licorice root extract(deglycyrrhized licorice) to fight for digestive distances, as a result of stress and bad dietary habits.
OciBest^® extracted from Ocimum Tenuflorium, is clinically tested to support stress management. In other words, OciBest^® is phytochemically standardized to Ociglycoside0.1%, rosmarinic acid 0.2%, and triterpene acids 2.5%.
Turmacin^® is from Turmeric and featured with water-soluble Turmerosaccharides^TM . Turmacin^®is an innovative clinically researched ingredient that brings the joint and cartilage health benefits of turmeric to dietary supplements.
ApBio^® and CalmCold^®: these two brands are why Natural Remedies are the top4 manufacturer on the Global, and Calmcold is for the European market.

ApBio^®-The fast-acting Andrographis Paniculata extracts to support immune health, and natural support to manage the symptoms of the common cold. The active compounds of Andrographis extract in ApBio^® are compliant with USP Pharmacopeia:

Andrographolide
Neoandrographolide
14-Deoxy-11,12-didehydroandrographolide
Andrograpanin

And the criteria/specification is the sum of the percentages of the 4 said diterpene lactones here before. For more info for proper formulation and other details, you may contact NaturalRemedy.

5. Patel Phyto Extractions PVT.LTD

K.Patel Phyto Extractions PVT.LTD is part of K.Patel Group, The group’s enterprise grew steadily over the last 5 decades and diversified into manufacturing of Basic Dyes and Chemicals, Pigments, Specialty Chemicals, Enamelled Copper Wires, and Real Estate business. K.Patel Phyto offers phytochemicals including Bacopa Monnieri(Brahmi) baccosides 10% to 50%, Ziniber officinale(Ginger) Total Gingerols 1% to 5% by HPLC,trifla extract total Tannin 20% to40%, Kalmegh extract andrographolides 10% to 50% and more. Meanwhile, KP also supplies other herbal extracts like bitters from Azadirachta indica with 1% to 5% and more.

K.Patel Phyto has 5 branded ingredients besides its phytochemicals and herbal extracts, which include the Andrographis Extract, branded as AndroPan^TM.In other words, AndroPan^TM is a Trademarked branded Ingredient of K. Patel Phyto Extractions Pvt. Ltd. And AndroPan^TM is a standardized extract of Andrographis having 40% Total Andrographolides content as per USP. The other 4 branded ingredients are

CurcuVail from Turmeric, the Indian spice
amVigour for Emblica officialis fruits extract
Ocitum for tulsi extract of the mint family
Tinofolia for a standardized extract of Tinospora cordifolia, standardized to Total Alkaloids and Total Terpenoids content.

Deep info of K.P, please visit their website to find more.

Top 6 Andrographis Extract Manufacturers in China.

With the literature of Traditional Chinese Medicine and Chinese Herb Medicine, more and more Chinese manufacturers combine the tradition with science. Besides the global market, there are also 5 China Andrographis extract manufacturers that you could consider. In China, the manufacturers focus on Guangxi and Sichuan provinces. Meanwhile, many companies have lengthened the product line to andrographolide derivatives Chuanhuning, Yanhuning, and andrographolide-sulfonate(Xiyanping) as active ingredients in the pharmaceutical, especially for injections.

1. Layn Ingredient Natural

We talked about Layn in the first part of the global market, Lay is a giant player in the Andrographis global market, and they generally focus on the international market of this extract.

2. Shanxi Jiaherb

JIAHERB is a cGMP, ISO series, Kosher and Halal certified company, dedicated to the identification, development, and manufacturing of botanical extracts and their derivatives. With strong R&D capabilities and advanced production technology, Jiaherb continues to make innovations with herbal extracts that service the Pharmaceutical, Nutraceutical, and Cosmetic industries. Firstly, JIAHERB runs several factories, more than 1000 staff, hundred series of products, 2 independent labs, more than 50 authorized patents. Moreover, Jiaherb’s certified lab is equipped with a state of the art instruments for test and identification, Such as UPLC, HPLC, UV(assay) and TT (for active components) GC and GC-MS (residue of solvents), ICP-MS (heavy metal), GC/LC-MS-MS (residue of pesticide), HPTLC and IR (identification), ELIASA (ORAC value), PSL (residue of irradiation), Microbiology test and etc. In addition, Jiaherb is a listed company in the Shanghai Stock exchange.

Based on Jiaherb’s technology and science, Jiaherb released 7 branded ingredients on the market:

Q10 pure for fermented Coenzyme Q10 from NSF cGMP certified facilities and certificates HACCP and others.
HTPURITY for 5-HTP, the Griffonia Simplicifolia seed extract with peak X free, NSF cGMP certified facilities and certificates HACCP and others.
Hydromeric for Turmeric extract and water-soluble curcumin, Hydromeric is certified by ¹⁴C test, HACCP,ISO22000, etc, developed in NSF cGMP certified facilities with three peaks.
Saw Palmetto Pure for Saw Palmetto extract extracted by CO₂in China GMP and NSF cGMP facilities, HACCP, ISO22000, and ISO9001 certified.
Trademark ReserveNature for nature-sourced resveratrol from grape skin or Polygonum Cuspidatum root. ReserveNature is developed in China GMP and NSF cGMP facilities, HACCP, ISO22000, and ISO9001 certified.
Trademark Q-DI95 for quercetin, botanically sourced from dry buds of Sophora Japonica. Quercetin is extracted in China GMP and NSF cGMP facilities, HACCP, ISO22000, and ISO9001 certified.
ThistleMarin for Milk Thistle Extract is mainly applied for liver protection, blood lipid reduction. Jiaherb’s milk thistle extract has DMF, approved by Korea FDA, has a Production license for silymarin drugs.

As to Andrographis extract, Jiaherb markets both domestic and overseas market, they are good at the Andrographis extract Androgapholide 50% HPLC with Kosher and Halal certificates. Jiaherb also has other Androgaphis specifications in its product portfolio. Jiaherb’s overseas market team is quite strong for the USA market for this herb.

Information in-depth is available by the Jiaherb team, contact them and inquire about it.

3. Sichuan Wenlong Pharmaceuticals Co., Ltd (Wenlong in short)

Wenlong was set up by Mr.Tu in 1996 and they focused on just one herb-The Andrographis Paniculata Nees. Meanwhile, Wenlong focuses on China’s domestic market only. 99% of the customers of Wenlong are pharmaceutical companies who make drugs and deliver them to the pharmacies.

Wenlong is a Chinese cGMP factory located in Nanxi county, Yibin, Sichuan. Sichuan is a province where the accurate extraction know-how and skills of Andrographis Extract are held. There are two workshop lines on the manufacturing site: the extraction line for Andrographolide and the semi-synthesis line for the Chuanhuning(Kalii Dehydrographolidi Succinas(DAS-K), CAS#:2216-51-5). Both these active compounds are registered API and are compliant with Chinese Pharmacopeia. Wenlong is the key player of API Andrographolide as Wenlong takes nearly 60% market of high content Andrographolide for the tablets(coated), drop-pills, and capsules. In addition, Wenlong’s registered API are welcomed by the Chuanhuning Injection manufacturers as Wenlong is one of the earlier initiators of API Chuanhuning.

Wenlong has its own Andrographis herbs plat base in both Sichuan and Guangdong province, Guangdong is the other top2 authentic place of Andrographis herbs.

It is hard to get more details about this factory on the website, but they may join some tradeshow in China.

4. Chengdu Tongde Pharmaceutical Co., Ltd (Tongde in Short)

Tongde is a China cGMP pharmaceutical company, set up in 1958 as state-owned Chengdu Third Biopharmaceutical Factory, rename Tongde in 2000. Tonde products line includes capsules, tablets, granules, lyophilized Injection, Injection, API, and plant extracts. The key products are:

Paracetamol Tablets
Injectable Pantoprazole Sodium
Heparin Sodium Injection, the Top 3 of domestic Market share
Coated Tablets-Pancreatic Kininogenase enteric
Oxytocin Injection
Andrographolide

As to Andrographis extract, the extraction line started running in 2015. It is the biggest monomer extraction line in domestic that year. This monomer line supports its semi-synthesis Chuanhuning workshop and makes them a big one in the API market for both Andrographis-related tablets, capsules, and the injection Chuanhuning. Furthermore, both Andrographolide and Androgapholide derivative-Chuanhuning are licensed API under the ChP and cGMP.

The main market of Tongde is the domestic human care field, they have not finished any export including the APIs.Details can be found on their website in Chinese.

5.Chengdu Benenature Biotech Co.,Ltd(Benenature in short)

Benenature is a top Andrographis extracts manufacturer and herbal extracts supplier since 2011. Benenature cultivates and selects the herbs from the native authentic site, and manufactures botanical extracts in Chengdu, Sichuan. Benenature has two extraction lines and a semi-synthesis workshop.

In the extraction lines, the following plant-based extracts are manufactured:

Andrographis Extract
Astragalas extract: astragaloside IV and polysaccarides
Sophora Japonica extract including Rutin and quercetin
Berberine Hydrochloride
Pannax Ginseng extract
Plant extract camptothecin and camptothecin derivatives

As to Andrographis extract, Benenature has the full specification and make them no clots within half a year:

Andrographis extract Andrographolide 5% by HPLC
Andrographolide 10% by HPLC
Andrographolide 30% by HPLC
Andrographolide 50% by HPLC
Andrographolide 98% by HPLC
Andrographolide 99% by HPLC

They strengthen their tech to Andrographolide derivatives also, and make the impurity to a strict level:

Chuanhuning, single impurity less than 0.5%
Yanhuning, or the water-soluble Andrographolide, intermediates level. Yanhuning is in fact Potassium Sodium Dehydroandrographolide Succinate.
Xiyanping(Andrographolide Sulfonate)

For more details please visit their website to get the ones you interested in.

6. Pengzhou Maoyuan Biochemical Technology Co., Ltd （Maoyuan in short）

Maoyuan was founded by Mr. Yang in 2006 with experienced extraction know-how. Maoyuan locates in Chengdu, Sichuan with two extraction lines and a semi-synthesis workshop.

Maoyuan is in Andrographis extraction for 10 years, they make the Guangxi-originated Andrographis herbs into Androgapholide 98% and Andrographolide99% for the domestic market, especially, Andrographolide99% are both for Chuanhuning and Yanhuning(Potassium Sodium Dehydroandrographolide Succinate).

Maoyuan is the top 1 player of camptothecin manufacturer in China, worldwide also. Maoyuan made camptothecin from both two nature sources: Mappi root and the happy tree leafs&fruits&roots. They are so skilled to make each impurity of both sourced camptothecin less than 0.1% HPLC respectively. In addition, Maoyuan lengthens the product line of camptothecin to10-hydroxy camptothecin,7-ethyl-10-hydroxy camptothecin,7-ethyl camptothecin, and they have mature know-how for the synthesis of the Irinotecan HCl from camptothecin and its derivative.

For more details please visit their website and get the inquires.

Make your best choice.

Which Andrographis Extract manufacturer fits you and your company more? Contact them directly and fulfill your sourcing task. Or still, feel confused, Benenature loves to do all out to meet your demands of Andrographis Extract.

What is Andrographis Extract?

Reference:

1.https://sabinsa.com/

2.https://www.martin-bauer-group.com/en/

3.www.layncorp.com

4.www.jiaherb.com

5.https://www.naturalremedy.com/

6.www.pzmybio.com

7.https://phytoextractskp.com/

8.http://www.cd-tdyy.com/

9.www.benenature.com

10.https://www.semanticscholar.org/paper/Nain-e-Havandi-Andrographis-paniculata-present-a-on-Valdiani-Kadir/e22396d1ba67a94213e209af73354f14fa725126/figure/0

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